Aronofsky is a misery monger

Patents are expiring next year for semaglutide

I wish I had some to hand but I tend to look them up ad hoc when I’m arguing with strangers for imaginary internet points

Yeah I agree it’s hard to say anything definitively. Especially if you are an armchair physician like me who read abstracts for random papers online.

I’ve read some studies that suggest people dying of lung cancer save the NHS money. They take up a lot of money in a lump sum but it tends to be incurable and kills them quite quickly. The alternative is people getting dementia or other degenerative cares and living for decades with round the clock care.

Oh well on the bright side we’ll save a lot of money on late life social care

I didn’t enjoy it that much. Found it overly sentimental and saccharine. Although to be fair I got the impression if I were a parent it would resonate with me more.

shit pushed in? Sign me up!

The Whale is probably going to be an artefact of its time very soon. Now that everyone has started on ozempic it was probably the last time they could film that story and have it be relatable/recognisable.

I got the light version of this as a joke birthday present. It plugs into a USB slot and makes an anemic light source. Haven’t used it much in summer but it might have some limited utility in winter.

le wrong generation. more like cRAP music, amirite?

Nabbed: Ninja Gaiden Collection, Auto Modellista, DOA6

Bonus game: Not really on sale (10% off) but Burggeist after seeing it in the new Iron Pineapple video. I’m a sucker for games inspired by Team Ico.

upvote: comment is interesting or funny

downvote: user is being rude (try not to downvote people I disagree with)

Thank you, Nintendo!

I think people find driving stressful because they struggle to operate machinery more than they are comfortable to admit

I do think that we are taking in too many people from around the world at the moment but I also think this sounds like a reasonable asylum claim. China does not treat its citizens well if they show any interest in politics.

They have people on talkshows every so often who claim to remember being born but they are clearly fantasists since consciousness doesn’t start in earnest until we are ~2.

Personally, it feels like I’ve got a limited amount of memory and the older I get the more years I cram into it. The early memories are starting to get crowded out.

The side-effects would need to be pretty extreme for the cost-benefit analysis to show using weight-loss drugs was more harmful than being obese.

I’m somewhat uncomfortable with the idea of muting some of our reward pathways in the brain though. Anecdotal reports so far have had people saying it has helped them with alcoholism and gambling in addition to losing weight, which makes me wonder if we’re using a sledgehammer to crack a walnut. At the same time I don’t have a genetic disposition towards gaining weight so maybe I’d have a different opinion if I’d tried everything else to lose weight and had felt out of options before these drugs came along.

Creep with me, as I cruise in my beemer,

All the kids in the ghetto running in fear,

My fat ass chasing them down the street,

AND fighting lawsuits that claim I’m a beast

Royal Tenenbaums would be my recommendation. It’s fairly close to the start of his ouevre but his style had been given a chance to develop a little bit by that point.